Protein folding and chart parsing
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چکیده
How can proteins fold so quickly into their unique native structures? We show here that there is a natural analogy between parsing and the protein folding problem, and demonstrate that CKY can find the native structures of a simplified lattice model of proteins with high accuracy.
منابع مشابه
Routes are trees: the parsing perspective on protein folding.
An important puzzle in structural biology is the question of how proteins are able to fold so quickly into their unique native structures. There is much evidence that protein folding is hierarchic. In that case, folding routes are not linear, but have a tree structure. Trees are commonly used to represent the grammatical structure of natural language sentences, and chart parsing algorithms effi...
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تاریخ انتشار 2006